|
Class id |
Class name |
Family size | E.Coli | S.cerevisiae | D.melanogaster | C.elegans | A.thaliana | O.sativa | H.sapiens | P. torridus | H. profundum | H. psychrophila | H. fumigatus | |||||||||||
| Num. | Percent | Num. | Percent | Num. | Percent | Num. | Percent | Num. | Percent | Num. | Percent | Num. | Percent | Num. | Percent | Num. | Percent | Num. | Percent | Num. | Percent | |||
| 1.A.1.9. | Voltage-gated ion channel | 6 | 0 | 0.00% | 0 | 0.00% | 10 | 0.63% | 48 | 3.23% | 0 | 0.00% | 0 | 0.00% | 14 | 0.78% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% |
| 1.A.10. | Glutamate-gated ion channel of neurotransmitter receptors GIC | 13 | 0 | 0.00% | 0 | 0.00% | 32 | 2.00% | 11 | 0.74% | 22 | 1.20% | 22 | 1.04% | 22 | 1.22% | 0 | 0.00% | 1 | 0.13% | 0 | 0.00% | 0 | 0.00% |
| 1.A.33. | Cation-channel-forming heat-shock protein 70 Hsp70 | 3 | 2 | 0.23% | 14 | 2.41% | 27 | 1.69% | 13 | 0.87% | 20 | 1.09% | 34 | 1.61% | 22 | 1.22% | 1 | 0.52% | 5 | 0.63% | 1 | 0.23% | 8 | 0.93% |
| 1.A.5. | Polycystin cation channel PCC | 3 | 0 | 0.00% | 0 | 0.00% | 13 | 0.81% | 7 | 0.47% | 0 | 0.00% | 0 | 0.00% | 40 | 2.22% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% |
| 1.A.6. | Epithelial Na+ channel ENaC | 15 | 0 | 0.00% | 0 | 0.00% | 27 | 1.69% | 34 | 2.28% | 0 | 0.00% | 0 | 0.00% | 16 | 0.89% | 0 | 0.00% | 1 | 0.13% | 0 | 0.00% | 0 | 0.00% |
| 1.A.8. | Major intrinsic protein MIP | 34 | 2 | 0.23% | 4 | 0.69% | 13 | 0.81% | 12 | 0.81% | 38 | 2.08% | 42 | 1.98% | 18 | 1.00% | 0 | 0.00% | 2 | 0.25% | 0 | 0.00% | 3 | 0.35% |
| 1.A.9. | Ligand-gated ion channel of neurotransmitter receptors LIC | 22 | 0 | 0.00% | 0 | 0.00% | 43 | 2.69% | 117 | 7.86% | 0 | 0.00% | 0 | 0.00% | 54 | 3.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% |
| 1.C.12. | Cholesterol-binding, thiol-activated cytolysin TAC | 9 | 0 | 0.00% | 0 | 0.00% | 5 | 0.31% | 67 | 4.50% | 0 | 0.00% | 0 | 0.00% | 31 | 1.72% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% |
| 1.x | Channels/pores | 118 | 13.64% | 43 | 7.39% | 390 | 24.41% | 539 | 36.22% | 224 | 12.24% | 237 | 11.19% | 610 | 33.87% | 5 | 2.59% | 85 | 10.63% | 32 | 7.24% | 37 | 4.28% | |
| 2.A.1.1. | Sugar porter SP | 58 | 7 | 0.81% | 33 | 5.67% | 53 | 3.32% | 23 | 1.55% | 66 | 3.61% | 69 | 3.26% | 18 | 1.00% | 18 | 9.33% | 1 | 0.13% | 0 | 0.00% | 77 | 8.91% |
| 2.A.1.14. | The Anion:Cation Symporter (ACS) Family | 19 | 7 | 0.81% | 8 | 1.37% | 35 | 2.19% | 55 | 3.70% | 9 | 0.49% | 8 | 0.38% | 7 | 0.39% | 1 | 0.52% | 0 | 0.00% | 2 | 0.45% | 34 | 3.94% |
| 2.A.1.19. | The Organic Cation Transporter (OCT) Family (The SLC22A family including OCT1-3, OCTN1-3 and OAT1-5 of H. sapiens) | 16 | 0 | 0.00% | 0 | 0.00% | 36 | 2.25% | 29 | 1.95% | 6 | 0.33% | 14 | 0.66% | 20 | 1.11% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 2 | 0.23% |
| 2.A.1.2. | Drug:H+ antiporter-1 (12 transmembrane segments) DHA1 | 38 | 28 | 3.24% | 17 | 2.92% | 18 | 1.13% | 24 | 1.61% | 19 | 1.04% | 29 | 1.37% | 17 | 0.94% | 16 | 8.29% | 11 | 1.38% | 5 | 1.13% | 81 | 9.38% |
| 2.A.1.3. | Drug:H+ antiporter-2 (14 transmembane segments) DHA2 | 29 | 3 | 0.35% | 7 | 1.20% | 0 | 0.00% | 1 | 0.07% | 1 | 0.05% | 0 | 0.00% | 1 | 0.06% | 8 | 4.15% | 5 | 0.63% | 3 | 0.68% | 31 | 3.59% |
| 2.A.17. | Proton-dependent oligopeptide transporter POT | 12 | 4 | 0.46% | 1 | 0.17% | 7 | 0.44% | 3 | 0.20% | 54 | 2.95% | 99 | 4.67% | 4 | 0.22% | 0 | 0.00% | 5 | 0.63% | 0 | 0.00% | 6 | 0.69% |
| 2.A.18. | Amino acid/auxin transporter (aka permease) AAAP | 25 | 0 | 0.00% | 7 | 1.20% | 27 | 1.69% | 11 | 0.74% | 49 | 2.68% | 57 | 2.69% | 14 | 0.78% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 14 | 1.62% |
| 2.A.22. | Neurotransmitter,Na+ symporter NSS | 26 | 0 | 0.00% | 0 | 0.00% | 38 | 2.38% | 15 | 1.01% | 0 | 0.00% | 0 | 0.00% | 20 | 1.11% | 0 | 0.00% | 3 | 0.38% | 1 | 0.23% | 0 | 0.00% |
| 2.A.29. | Mitochondrial carrier MC | 65 | 0 | 0.00% | 30 | 5.15% | 77 | 4.82% | 38 | 2.55% | 64 | 3.50% | 72 | 3.40% | 61 | 3.39% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 37 | 4.28% |
| 2.A.3.1. | Amino acid transporter AAT | 13 | 11 | 1.27% | 0 | 0.00% | 0 | 0.00% | 1 | 0.07% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 7 | 3.63% | 0 | 0.00% | 2 | 0.45% | 2 | 0.23% |
| 2.A.3.10. | Yeast amino acid transporter YAT | 20 | 0 | 0.00% | 18 | 3.09% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 1 | 0.52% | 0 | 0.00% | 0 | 0.00% | 12 | 1.39% |
| 2.A.3.4. | Amino acid/choline transporter ACT | 5 | 0 | 0.00% | 4 | 0.69% | 0 | 0.00% | 0 | 0.00% | 2 | 0.11% | 8 | 0.38% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 20 | 2.31% |
| 2.A.56. | Tripartite ATP-independent periplasmic transporter TRAP-T | 20 | 1 | 0.12% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 15 | 1.88% | 17 | 3.85% | 0 | 0.00% |
| 2.A.66. | Multi-antimicrobial extrusion factor MATE | 38 | 5 | 0.58% | 3 | 0.52% | 1 | 0.06% | 1 | 0.07% | 54 | 2.95% | 39 | 1.84% | 3 | 0.17% | 1 | 0.52% | 10 | 1.25% | 3 | 0.68% | 2 | 0.23% |
| 2.A.7.4. | Plant drug/metabolite exporter P-DME | 2 | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 61 | 3.33% | 62 | 2.93% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% |
| 2.x | Secondary carriers | 233 | 26.94% | 213 | 36.60% | 549 | 34.36% | 454 | 30.51% | 752 | 41.09% | 886 | 41.83% | 428 | 23.76% | 75 | 38.86% | 221 | 27.63% | 112 | 25.34% | 464 | 53.70% | |
| 3.A.1.1. | Carbohydrate importer-1 CUT1 | 102 | 12 | 1.39% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 15 | 7.77% | 10 | 1.25% | 0 | 0.00% | 0 | 0.00% |
| 3.A.1.120. | Drug resistance ATPase-1 Drug RA1 | 5 | 10 | 1.16% | 8 | 1.37% | 6 | 0.38% | 5 | 0.34% | 14 | 0.77% | 21 | 0.99% | 5 | 0.28% | 4 | 2.07% | 10 | 1.25% | 8 | 1.81% | 9 | 1.04% |
| 3.A.1.2. | Carbohydrate importer-2 CUT2 | 41 | 31 | 3.58% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 2 | 0.09% | 0 | 0.00% | 0 | 0.00% | 20 | 2.50% | 6 | 1.36% | 0 | 0.00% |
| 3.A.1.204. | Eye pigment precuror transporter EPP | 7 | 0 | 0.00% | 2 | 0.34% | 32 | 2.00% | 10 | 0.67% | 36 | 1.97% | 38 | 1.79% | 11 | 0.61% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 6 | 0.69% |
| 3.A.1.3. | Polar amino acid importer PAAT | 60 | 24 | 2.77% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 24 | 3.00% | 22 | 4.98% | 0 | 0.00% |
| 3.A.1.4. | Hydrophobic amino acid importer HAAT | 30 | 6 | 0.69% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 9 | 2.04% | 0 | 0.00% |
| 3.A.1.5. | Peptide/opine/nickel importer PepT | 74 | 35 | 4.05% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 14 | 7.25% | 31 | 3.88% | 14 | 3.17% | 0 | 0.00% |
| 3.A.15. | The Outer Membrane Protein Secreting Main Terminal Branch (MTB) Family | 24 | 3 | 0.35% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 17 | 2.13% | 5 | 1.13% | 0 | 0.00% |
| 3.A.16. | The Endoplasmic Reticular Retrotranslocon (ER-RT) Family | 9 | 1 | 0.12% | 21 | 3.61% | 39 | 2.44% | 38 | 2.55% | 68 | 3.72% | 76 | 3.59% | 38 | 2.11% | 1 | 0.52% | 1 | 0.13% | 1 | 0.23% | 20 | 2.31% |
| 3.A.18. | The Nuclear mRNA Exporter (mRNA-E) Family | 13 | 5 | 0.58% | 25 | 4.30% | 53 | 3.32% | 49 | 3.29% | 74 | 4.04% | 98 | 4.63% | 75 | 4.16% | 1 | 0.52% | 10 | 1.25% | 5 | 1.13% | 24 | 2.78% |
| 3.A.2.1. | H+- or Na+-translocating F-type, V-type and A-type ATPase superfamily F-ATPase | 28 | 8 | 0.92% | 12 | 2.06% | 10 | 0.63% | 11 | 0.74% | 10 | 0.55% | 13 | 0.61% | 9 | 0.50% | 0 | 0.00% | 16 | 2.00% | 6 | 1.36% | 7 | 0.81% |
| 3.A.2.2. | H+- or Na+-translocating F-type, V-type and A-type ATPase superfamily F-ATPase | 39 | 0 | 0.00% | 15 | 2.58% | 47 | 2.94% | 25 | 1.68% | 28 | 1.53% | 24 | 1.13% | 28 | 1.55% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 12 | 1.39% |
| 3.A.6. | Type III (virulence-related) secretory pathway IIISP | 12 | 20 | 2.31% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 15 | 1.88% | 8 | 1.81% | 0 | 0.00% |
| 3.A.7. | Type IV (conjugal DNA-protein transfer) secretory pathway IVSP | 142 | 2 | 0.23% | 0 | 0.00% | 0 | 0.00% | 1 | 0.07% | 2 | 0.11% | 1 | 0.05% | 1 | 0.06% | 1 | 0.52% | 10 | 1.25% | 9 | 2.04% | 0 | 0.00% |
| 3.A.8. | Mitochondrial protein translocating system (Tim-Tom) MPT | 24 | 0 | 0.00% | 28 | 4.81% | 27 | 1.69% | 13 | 0.87% | 24 | 1.31% | 26 | 1.23% | 21 | 1.17% | 0 | 0.00% | 1 | 0.13% | 1 | 0.23% | 20 | 2.31% |
| 3.A.9. | Chloroplast protein translocating system (Tic-Toc) CEPT | 10 | 0 | 0.00% | 4 | 0.69% | 3 | 0.19% | 4 | 0.27% | 32 | 1.75% | 46 | 2.17% | 5 | 0.28% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 11 | 1.27% |
| 3.D.1. | Proton-translocating NADH dehydrogenase NDH | 81 | 23 | 2.66% | 0 | 0.00% | 15 | 0.94% | 11 | 0.74% | 10 | 0.55% | 20 | 0.94% | 12 | 0.67% | 13 | 6.74% | 0 | 0.00% | 16 | 3.62% | 7 | 0.81% |
| 3.D.4.8. | Proton-translocating cytochrome oxidase superfamily COX | 15 | 0 | 0.00% | 17 | 2.92% | 5 | 0.31% | 4 | 0.27% | 4 | 0.22% | 3 | 0.14% | 3 | 0.17% | 0 | 0.00% | 1 | 0.13% | 0 | 0.00% | 8 | 0.93% |
| 3.D.7. | H2-heterodisulfide oxidoreductase HHO | 7 | 4 | 0.46% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 1 | 0.13% | 11 | 2.49% | 0 | 0.00% |
| 3.x | Active transporters | 319 | 36.88% | 201 | 34.54% | 407 | 25.47% | 304 | 20.43% | 491 | 26.83% | 606 | 28.61% | 400 | 22.21% | 90 | 46.63% | 323 | 40.38% | 208 | 47.06% | 207 | 23.96% | |
| 4.x | Group translocators | 45 | 5.20% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 29 | 3.63% | 0 | 0.00% | 0 | 0.00% | |
| 5.A.3. | The Prokaryotic Molybdopterin-containing Oxidoreductase (PMO) Family | 54 | 43 | 4.97% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 2 | 1.04% | 26 | 3.25% | 10 | 2.26% | 1 | 0.12% |
| 5.B.4. | The Plant Photosystem I Supercomplex (PSI) Family | 15 | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 38 | 2.08% | 43 | 2.03% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% |
| 5.x | Electron carriers | 45 | 5.20% | 6 | 1.03% | 11 | 0.69% | 4 | 0.27% | 61 | 3.33% | 66 | 3.12% | 15 | 0.83% | 2 | 1.04% | 29 | 3.63% | 11 | 2.49% | 7 | 0.81% | |
| 8.A.30. | The Nedd4-Family Interacting Protein-2 (Nedd4) Family | 2 | 0 | 0.00% | 7 | 1.20% | 47 | 2.94% | 37 | 2.49% | 37 | 2.02% | 45 | 2.12% | 86 | 4.78% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 8 | 0.93% |
| 8.A.5. | Voltage-gated K+ channel b-subunit VICb | 3 | 6 | 0.69% | 1 | 0.17% | 4 | 0.25% | 5 | 0.34% | 6 | 0.33% | 15 | 0.71% | 7 | 0.39% | 4 | 2.07% | 1 | 0.13% | 0 | 0.00% | 7 | 0.81% |
| 8.x | Accessory factors | 26 | 3.01% | 20 | 3.44% | 95 | 5.94% | 67 | 4.50% | 65 | 3.55% | 91 | 4.30% | 164 | 9.11% | 8 | 4.15% | 21 | 2.63% | 12 | 2.71% | 29 | 3.36% | |
| 9.A.14. | Nuclear pore complex NPC | 33 | 0 | 0.00% | 42 | 7.22% | 38 | 2.38% | 33 | 2.22% | 51 | 2.79% | 34 | 1.61% | 57 | 3.16% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 16 | 1.85% |
| 9.A.34. | The Putative Type VI Symbiosis/Virulence Secretory Pathway (VISP) Family | 12 | 22 | 2.54% | 2 | 0.34% | 0 | 0.00% | 0 | 0.00% | 8 | 0.44% | 14 | 0.66% | 1 | 0.06% | 0 | 0.00% | 22 | 2.75% | 24 | 5.43% | 2 | 0.23% |
| 9.A.5. | Peroxisomal protein importer PPI | 10 | 0 | 0.00% | 18 | 3.09% | 29 | 1.81% | 17 | 1.14% | 34 | 1.86% | 35 | 1.65% | 36 | 2.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 21 | 2.43% |
| 9.B.17. | The Putative Fatty Acid Transporter (FAT) Family | 7 | 8 | 0.92% | 10 | 1.72% | 43 | 2.69% | 31 | 2.08% | 51 | 2.79% | 54 | 2.55% | 33 | 1.83% | 5 | 2.59% | 16 | 2.00% | 8 | 1.81% | 44 | 5.09% |
| 9.B.32. | The Putative Vectorial Glycosyl Polymerization (VGP) Family | 4 | 5 | 0.58% | 3 | 0.52% | 0 | 0.00% | 1 | 0.07% | 5 | 0.27% | 3 | 0.14% | 3 | 0.17% | 4 | 2.07% | 6 | 0.75% | 3 | 0.68% | 2 | 0.23% |
| 9.x | Incompletely characterized | 79 | 9.13% | 99 | 17.01% | 146 | 9.14% | 120 | 8.06% | 237 | 12.95% | 232 | 10.95% | 184 | 10.22% | 13 | 6.74% | 92 | 11.50% | 67 | 15.16% | 120 | 13.89% | |
| Total | 39.08% | 62.03% | 53.82% | 54.10% | 54.48% | 55.05% | 45.14% | 60.62% | 37.13% | 45.25% | 64.12% | |||||||||||||
| Class id | Class name | Family size | E coli | S. cerevisa | D. melanogaster | C. elegans | A. thaliana | O. sativa | H. sapiens | P. torridus | P. profundum | D. psychrophila | A. fumigatus | average | |||||||||||
| Num. | Percent | Num. | Percent | Num. | Percent | Num. | Percent | Num. | Percent | Num. | Percent | Num. | Percent | Num. | Percent | Num. | Percent | Num. | Percent | Num. | Percent | ||||
| 1.A.1.9. | Voltage-gated ion channel | 6 | 0 | 0.00% | 0 | 0.00% | 8 | 80.00% | 44 | 92.00% | 0 | 0.00% | 0 | 0.00% | 14 | 100.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 91.67% |
| 1.A.10. | Glutamate-gated ion channel of neurotransmitter receptors GIC | 13 | 0 | 0.00% | 0 | 0.00% | 26 | 81.00% | 8 | 73.00% | 21 | 95.00% | 22 | 100.00% | 22 | 100.00% | 0 | 0.00% | 1 | 100.00% | 0 | 0.00% | 0 | 0.00% | 90.91% |
| 1.A.33. | Cation-channel-forming heat-shock protein 70 Hsp70 | 3 | 1 | 50.00% | 1 | 7.00% | 12 | 44.00% | 1 | 8.00% | 8 | 40.00% | 21 | 62.00% | 14 | 64.00% | 0 | 0.00% | 1 | 20.00% | 0 | 0.00% | 8 | 100.00% | 45.58% |
| 1.A.5. | Polycystin cation channel PCC | 3 | 0 | 0.00% | 0 | 0.00% | 2 | 15.00% | 1 | 14.00% | 0 | 0.00% | 0 | 0.00% | 9 | 23.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 20.00% |
| 1.A.6. | Epithelial Na+ channel ENaC | 15 | 0 | 0.00% | 0 | 0.00% | 19 | 70.00% | 18 | 53.00% | 0 | 0.00% | 0 | 0.00% | 14 | 88.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 65.38% |
| 1.A.8. | Major intrinsic protein MIP | 34 | 2 | 100.00% | 4 | 100.00% | 13 | 100.00% | 7 | 58.00% | 37 | 97.00% | 42 | 100.00% | 12 | 67.00% | 0 | 0.00% | 2 | 100.00% | 0 | 0.00% | 3 | 100.00% | 91.04% |
| 1.A.9. | Ligand-gated ion channel of neurotransmitter receptors LIC | 22 | 0 | 0.00% | 0 | 0.00% | 39 | 91.00% | 81 | 69.00% | 0 | 0.00% | 0 | 0.00% | 50 | 93.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 79.44% |
| 1.C.12. | Cholesterol-binding, thiol-activated cytolysin TAC | 9 | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0.00% |
| 1.x | Channels/pores | 60 | 50.85% | 18 | 41.86% | 260 | 66.67% | 308 | 57.14% | 149 | 66.52% | 158 | 66.67% | 456 | 74.75% | 3 | 60.00% | 32 | 37.65% | 12 | 37.50% | 31 | 83.78% | 58.49% | |
| 2.A.1.1. | Sugar porter SP | 58 | 7 | 100.00% | 32 | 97.00% | 48 | 91.00% | 17 | 74.00% | 66 | 100.00% | 69 | 100.00% | 18 | 100.00% | 18 | 100.00% | 1 | 100.00% | 0 | 0.00% | 77 | 100.00% | 96.71% |
| 2.A.1.14. | The Anion:Cation Symporter (ACS) Family | 19 | 7 | 100.00% | 8 | 100.00% | 34 | 97.00% | 45 | 82.00% | 9 | 100.00% | 8 | 100.00% | 5 | 71.00% | 1 | 100.00% | 0 | 0.00% | 0 | 0.00% | 32 | 94.00% | 89.76% |
| 2.A.1.19. | The Organic Cation Transporter (OCT) Family (The SLC22A family including OCT1-3, OCTN1-3 and OAT1-5 of H. sapiens) | 16 | 0 | 0.00% | 0 | 0.00% | 36 | 100.00% | 22 | 76.00% | 6 | 100.00% | 14 | 100.00% | 20 | 100.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 2 | 100.00% | 93.46% |
| 2.A.1.2. | Drug:H+ antiporter-1 (12 transmembrane segments) DHA1 | 38 | 28 | 100.00% | 17 | 100.00% | 14 | 78.00% | 18 | 75.00% | 15 | 79.00% | 28 | 97.00% | 16 | 94.00% | 16 | 100.00% | 11 | 100.00% | 5 | 100.00% | 70 | 86.00% | 89.81% |
| 2.A.1.3. | Drug:H+ antiporter-2 (14 transmembane segments) DHA2 | 29 | 3 | 100.00% | 7 | 100.00% | 0 | 0.00% | 1 | 100.00% | 1 | 100.00% | 0 | 0.00% | 1 | 100.00% | 8 | 100.00% | 5 | 100.00% | 3 | 100.00% | 28 | 90.00% | 95.00% |
| 2.A.17. | Proton-dependent oligopeptide transporter POT | 12 | 4 | 100.00% | 1 | 100.00% | 7 | 100.00% | 3 | 100.00% | 54 | 100.00% | 98 | 99.00% | 4 | 100.00% | 0 | 0.00% | 5 | 100.00% | 0 | 0.00% | 6 | 100.00% | 99.45% |
| 2.A.18. | Amino acid/auxin transporter (aka permease) AAAP | 25 | 0 | 0.00% | 7 | 100.00% | 27 | 100.00% | 9 | 82.00% | 49 | 100.00% | 57 | 100.00% | 14 | 100.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 14 | 100.00% | 98.88% |
| 2.A.22. | Neurotransmitter,Na+ symporter NSS | 26 | 0 | 0.00% | 0 | 0.00% | 37 | 97.00% | 14 | 93.00% | 0 | 0.00% | 0 | 0.00% | 18 | 90.00% | 0 | 0.00% | 3 | 100.00% | 1 | 100.00% | 0 | 0.00% | 94.81% |
| 2.A.29. | Mitochondrial carrier MC | 65 | 0 | 0.00% | 28 | 93.00% | 64 | 83.00% | 34 | 89.00% | 56 | 88.00% | 70 | 97.00% | 52 | 85.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 36 | 97.00% | 89.71% |
| 2.A.3.1. | Amino acid transporter AAT | 13 | 11 | 100.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 7 | 100.00% | 0 | 0.00% | 2 | 100.00% | 2 | 100.00% | 95.65% |
| 2.A.3.10. | Yeast amino acid transporter YAT | 20 | 0 | 0.00% | 18 | 100.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 1 | 100.00% | 0 | 0.00% | 0 | 0.00% | 12 | 100.00% | 100.00% |
| 2.A.3.4. | Amino acid/choline transporter ACT | 5 | 0 | 0.00% | 4 | 100.00% | 0 | 0.00% | 0 | 0.00% | 2 | 100.00% | 8 | 100.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 20 | 100.00% | 100.00% |
| 2.A.56. | Tripartite ATP-independent periplasmic transporter TRAP-T | 20 | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 15 | 100.00% | 17 | 100.00% | 0 | 0.00% | 96.97% |
| 2.A.66. | Multi-antimicrobial extrusion factor MATE | 38 | 5 | 100.00% | 3 | 100.00% | 0 | 0.00% | 0 | 0.00% | 54 | 100.00% | 39 | 100.00% | 2 | 67.00% | 1 | 100.00% | 10 | 100.00% | 3 | 100.00% | 1 | 50.00% | 96.72% |
| 2.A.7.4. | Plant drug/metabolite exporter P-DME | 2 | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 61 | 100.00% | 59 | 95.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 97.56% |
| 2.x | Secondary carriers | 218 | 93.56% | 199 | 93.43% | 485 | 88.34% | 352 | 77.53% | 699 | 92.95% | 847 | 95.60% | 378 | 88.32% | 73 | 97.33% | 209 | 94.57% | 106 | 94.64% | 429 | 92.46% | 91.70% | |
| 3.A.1.1. | Carbohydrate importer-1 CUT1 | 102 | 12 | 100.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 15 | 100.00% | 10 | 100.00% | 0 | 0.00% | 0 | 0.00% | 100.00% |
| 3.A.1.120. | Drug resistance ATPase-1 Drug RA1 | 5 | 8 | 80.00% | 2 | 25.00% | 0 | 0.00% | 1 | 20.00% | 6 | 43.00% | 7 | 33.00% | 0 | 0.00% | 1 | 25.00% | 10 | 100.00% | 8 | 100.00% | 1 | 11.00% | 44.00% |
| 3.A.1.2. | Carbohydrate importer-2 CUT2 | 41 | 30 | 97.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 2 | 100.00% | 0 | 0.00% | 0 | 0.00% | 19 | 95.00% | 6 | 100.00% | 0 | 0.00% | 96.61% |
| 3.A.1.204. | Eye pigment precuror transporter EPP | 7 | 0 | 0.00% | 2 | 100.00% | 32 | 100.00% | 8 | 80.00% | 36 | 100.00% | 38 | 100.00% | 11 | 100.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 6 | 100.00% | 98.52% |
| 3.A.1.3. | Polar amino acid importer PAAT | 60 | 24 | 100.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 24 | 100.00% | 22 | 100.00% | 0 | 0.00% | 100.00% |
| 3.A.1.4. | Hydrophobic amino acid importer HAAT | 30 | 6 | 100.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 9 | 100.00% | 0 | 0.00% | 100.00% |
| 3.A.1.5. | Peptide/opine/nickel importer PepT | 74 | 35 | 100.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 14 | 100.00% | 31 | 100.00% | 14 | 100.00% | 0 | 0.00% | 100.00% |
| 3.A.15. | The Outer Membrane Protein Secreting Main Terminal Branch (MTB) Family | 24 | 1 | 33.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 4.00% |
| 3.A.16. | The Endoplasmic Reticular Retrotranslocon (ER-RT) Family | 9 | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 1 | 3.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0.33% |
| 3.A.18. | The Nuclear mRNA Exporter (mRNA-E) Family | 13 | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 2 | 4.00% | 0 | 0.00% | 1 | 1.00% | 15 | 20.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 4.30% |
| 3.A.2.1. | H+- or Na+-translocating F-type, V-type and A-type ATPase superfamily F-ATPase | 28 | 8 | 100.00% | 9 | 75.00% | 10 | 100.00% | 7 | 64.00% | 8 | 80.00% | 12 | 92.00% | 8 | 89.00% | 0 | 0.00% | 16 | 100.00% | 6 | 100.00% | 7 | 100.00% | 89.22% |
| 3.A.2.2. | H+- or Na+-translocating F-type, V-type and A-type ATPase superfamily F-ATPase | 39 | 0 | 0.00% | 12 | 80.00% | 47 | 100.00% | 16 | 64.00% | 28 | 100.00% | 21 | 88.00% | 28 | 100.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 12 | 100.00% | 91.62% |
| 3.A.6. | Type III (virulence-related) secretory pathway IIISP | 12 | 4 | 20.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 9.30% |
| 3.A.7. | Type IV (conjugal DNA-protein transfer) secretory pathway IVSP | 142 | 1 | 50.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 2 | 100.00% | 1 | 100.00% | 0 | 0.00% | 0 | 0.00% | 5 | 50.00% | 7 | 78.00% | 0 | 0.00% | 59.26% |
| 3.A.8. | Mitochondrial protein translocating system (Tim-Tom) MPT | 24 | 0 | 0.00% | 18 | 64.00% | 10 | 37.00% | 2 | 15.00% | 3 | 12.00% | 11 | 42.00% | 10 | 48.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 13 | 65.00% | 41.61% |
| 3.A.9. | Chloroplast protein translocating system (Tic-Toc) CEPT | 10 | 0 | 0.00% | 0 | 0.00% | 2 | 67.00% | 0 | 0.00% | 1 | 3.00% | 13 | 28.00% | 1 | 20.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 16.19% |
| 3.D.1. | Proton-translocating NADH dehydrogenase NDH | 81 | 15 | 65.00% | 0 | 0.00% | 3 | 20.00% | 6 | 55.00% | 9 | 90.00% | 9 | 45.00% | 12 | 100.00% | 10 | 77.00% | 0 | 0.00% | 9 | 56.00% | 6 | 86.00% | 62.20% |
| 3.D.4.8. | Proton-translocating cytochrome oxidase superfamily COX | 15 | 0 | 0.00% | 13 | 76.00% | 0 | 0.00% | 0 | 0.00% | 2 | 50.00% | 2 | 67.00% | 2 | 67.00% | 0 | 0.00% | 1 | 100.00% | 0 | 0.00% | 5 | 62.00% | 55.56% |
| 3.D.7. | H2-heterodisulfide oxidoreductase HHO | 7 | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0.00% |
| 3.x | Active transporters | 257 | 80.56% | 105 | 52.24% | 224 | 55.04% | 113 | 37.17% | 242 | 49.29% | 303 | 50.00% | 228 | 57.00% | 72 | 80.00% | 248 | 76.78% | 152 | 73.08% | 116 | 56.04% | 60.65% | |
| 4.x | Group translocators | 45 | 100.00% | 0 | N/A | 0 | N/A | 0 | N/A | 0 | N/A | 0 | N/A | 0 | N/A | 0 | N/A | 29 | N/A | 0 | N/A | 0 | N/A | N/A | |
| 5.A.3. | The Prokaryotic Molybdopterin-containing Oxidoreductase (PMO) Family | 54 | 8 | 19.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 2 | 20.00% | 0 | 0.00% | 12.20% |
| 5.B.4. | The Plant Photosystem I Supercomplex (PSI) Family | 15 | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 38 | 100.00% | 16 | 37.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 66.67% |
| 5.x | Electron carriers | 8 | 17.78% | 0 | 0.00% | 2 | 18.18% | 0 | 0.00% | 42 | 68.85% | 35 | 53.03% | 13 | 86.67% | 0 | 0.00% | 0 | 0.00% | 2 | 18.18% | 1 | 14.29% | 25.18% | |
| 8.A.30. | The Nedd4-Family Interacting Protein-2 (Nedd4) Family | 2 | 0 | 0.00% | 0 | 0.00% | 4 | 9.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 15 | 17.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 7.12% |
| 8.A.5. | Voltage-gated K+ channel b-subunit VICb | 3 | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 1 | 17.00% | 1 | 7.00% | 6 | 86.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 14.29% |
| 8.x | Accessory factors | 2 | 7.69% | 0 | 0.00% | 11 | 11.58% | 13 | 19.40% | 1 | 1.54% | 4 | 4.40% | 76 | 46.34% | 1 | 12.50% | 2 | 9.52% | 1 | 8.33% | 0 | 0.00% | 11.03% | |
| 9.A.14. | Nuclear pore complex NPC | 33 | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 6 | 18.00% | 0 | 0.00% | 0 | 0.00% | 4 | 7.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 6 | 38.00% | 5.90% |
| 9.A.34. | The Putative Type VI Symbiosis/Virulence Secretory Pathway (VISP) Family | 12 | 1 | 5.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 2 | 9.00% | 0 | 0.00% | 0 | 0.00% | 3.16% |
| 9.A.5. | Peroxisomal protein importer PPI | 10 | 0 | 0.00% | 0 | 0.00% | 6 | 21.00% | 0 | 0.00% | 0 | 0.00% | 4 | 11.00% | 8 | 22.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 3 | 14.00% | 11.05% |
| 9.B.17. | The Putative Fatty Acid Transporter (FAT) Family | 7 | 1 | 12.00% | 2 | 20.00% | 2 | 5.00% | 3 | 10.00% | 7 | 14.00% | 0 | 0.00% | 17 | 52.00% | 1 | 20.00% | 5 | 31.00% | 2 | 25.00% | 2 | 5.00% | 13.86% |
| 9.B.32. | The Putative Vectorial Glycosyl Polymerization (VGP) Family | 4 | 1 | 20.00% | 0 | 0.00% | 0 | 0.00% | 0 | 0.00% | 4 | 80.00% | 3 | 100.00% | 0 | 0.00% | 3 | 75.00% | 3 | 50.00% | 2 | 67.00% | 0 | 0.00% | 45.71% |
| 9.x | Incompletely characterized | 13 | 16.46% | 5 | 5.05% | 9 | 6.16% | 11 | 9.17% | 13 | 5.49% | 18 | 7.76% | 35 | 19.02% | 6 | 46.15% | 20 | 21.74% | 11 | 16.42% | 17 | 14.17% | 15.23% | |